Fig. 1
From: Non-genomic regulation and disruption of spermatozoal in vitro hyperactivation by oviductal hormones
Hypothesized mechanism for the regulation of hyperactivation enhancement by progesterone and estradiol. AC adenylate cyclase, ATP adenosine triphosphate, CAMK calmodulin-dependent protein kinase, cAMP cyclic adenosine monophosphate, DAG diacylglycerol, E estradiol, ER estrogen receptor, IP 3 inositol 1,4,5-tris–phosphate, IP 3 R inositol 1,4,5-tris–phosphate receptor, P progesterone, PC phosphatidylcholine, PI phosphatidylinositol, PKA protein kinase A, PKC protein kinase C, PLC phospholipase C, PR progesterone receptor, PTK protein tyrosine kinase