Fig. 4
From: Frontier studies on fatigue, autonomic nerve dysfunction, and sleep-rhythm disorder
The brain regions involved in the neural mechanisms of fatigue sensation and those of classical conditioning of fatigue sensation. The neural mechanisms of fatigue sensation, which constitute the inhibition system of fatigue, include the posterior cingulate and insular cortices. The posterior cingulate and insular cortices are also involved in the neural mechanisms of the classical conditioning of fatigue sensation