Fig. 5
From: Delayed onset muscle soreness: Involvement of neurotrophic factors
Schematic diagram of the mechanism proposed for DOMS. The upper part of the figure in the shaded area was based on Boix et al. [59]. BK, bradykinin-like substance (Arg-bradykinin in rats); COX2, cyclooxygenase-2; PGs, prostaglandins; EP2, prostaglandin EP2 receptor; GDNF, glial cell line-derived neurotrophic factor; NGF, nerve growth factor; ASIC, acid sensing ion channel; TRPV1 and TRPV4 transient receptor potential vanilloids 1 and 4. Modified from Mizumura et al. [79]