Fig. 1
From: Neurophysiological modeling of bladder afferent activity in the rat overactive bladder model
Experimental set-up. After exposing the abdominal cavity, a 23G needle was inserted at the top of the bladder for filling and pressure measurement. The other end of the needle was attached to a disposable pressure transducer and an infusion pump using a 2-way connector. Custom-made bipolar electrodes consisting of two thin platinum–iridium hook shaped wires separated by a distance of 0.5–1 mm were placed under one of the branches of the pelvic nerve using a micromanipulator. The recorded nerve signal was then amplified and band pass filtered