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Fig. 1 | The Journal of Physiological Sciences

Fig. 1

From: Ex vivo cultured neuronal networks emit in vivo-like spontaneous activity

Fig. 1

Comparison of the spontaneous firing rates of CA1 neurons between the in vivo, cultured, and acute hippocampal network. Representative traces of in vivo cell-attached recording (a) and calcium imaging from the CA1 and CA3 pyramidal cell layer in a slice culture (b) and an acute slice (c). Orange dots below the traces indicate the timings of spikes. d The mean ± SD firing rates of 175 CA1 neurons of in vivo preparations (red), 1,178 neurons from 12 slice cultures (blue), and 1,056 neurons from 15 acute slices (green). ***P < 0.001, median test

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