Table 1 Summary of changes in peak currents and pulse-end currents after application of NSAIDs and macrolide antibiotics
NSAIDs | N | Peak current (%) | Pulse-end current/peak current (I/I peak) (%) | ||
|---|---|---|---|---|---|
Before | After | Before | After | ||
0.1 mM Diclofenac Na | 5 | 100 | 94.5 ± 4.3 | 42.0 ± 1.4 | 17.0 ± 1.9# |
0.3 mM Salicylate | 5 | 100 | 89.8 ± 3.2 | 52.2 ± 3.9 | 20.8 ± 2.9# |
0.1 mM Indomethacin | 5 | 100 | 75.9 ± 4.8# | 44.3 ± 7.4 | 29.3 ± 1.7# |
NSAIDs | N | Peak current density (pA/pF) | Pulse-end current/peak current (I/I peak) (%) | ||
|---|---|---|---|---|---|
Before | After | Before | After | ||
30 μM Clarithromycin | 5 | 178 ± 5.6 | 111 ± 2.0# | 47.5 ± 2.2 | 15.5 ± 3.3# |
100 μM Clarithromycin | 5 | 277 ± 4.4 | 89.6 ± 10# | 48.5 ± 1.4 | 15.8 ± 1.0# |