Fig. 4
From: Potential role of transient receptor potential (TRP) channels in bladder cancer cells
Proliferation of MBT-2 cells expressing TRPV2 and TRPM7. a Effects of dominant-negative TRPV2, full-length TRPV2, and full-length TRPM7 on the proliferation of MBT-2 cells, as assessed with MTS assays. Cell numbers were normalized to values in the control (mock-transfected) cells. V2DN, cells expressing dominant-negative TRPV2; V2, cells expressing full-length TRPV2; M7, cells expressing full-length TRPM7. Bars ± SEM (n = 6), *p = 0.02, **p < 0.001. b Effects of TRPV2 activators on MBT-2 cell proliferation. LPC (30 μM) or 2-APB (100 μM) was added 24 h before MTS assay (*p < 0.001, n = 6; **p = 0.007, n = 6). Bars ± SEM