Fig. 2From: Potential role of transient receptor potential (TRP) channels in bladder cancer cellsChanges in cytosolic Ca2+ concentrations in response to agonist application in urothelial cells from C3H/HeN mice and MBT-2 cells. a–f Changes in cytosolic Ca2+ concentrations (indicated by the 340/380 nm excitation ratio, with SEM) in response to TRPV2 agonists (2-APB and LPC; a–d) or a TRPV4 agonist [GSK1016790A (GSK); e, f] in urothelial cells from C3H/HeN mice (left) and in MBT-2 cells (right). Bars indicate the time of agonist application. g Differences in changes of cytosolic Ca2+ concentrations (delta ratio %: difference between the basal values and peak values normalized to that of ionomycin) between urothelial cells from C3H/HeN mice and MBT-2 cells. n = 100–130 in three independent experiments. *, **p < 0.05, p < 0.01 vs. C3H/HeN. Iono ionomycinBack to article page