Fig. 3
From: The protective effect of apelin against water-immersion and restraint stress-induced gastric damage
Effect of F13A (APJ receptor antagonist) on the HIF1-α expression in rat gastric mucosa subjected to water-immersion and restraint stress (WIRS). F13A (150 µg/kg) was administered into the tail vein before the application of WIRS. After 6 h of WIRS, the HIF1-α expression in gastric mucosa was determined as described in “Materials and methods.” a Shows stomach specimen of control, b shows stomach specimen of WIRS group, c shows stomach specimen of F13A + WIRS, d shows stomach specimen of F13A and e shows HIF1-α H scores of groups. The results are the mean ± SD of 6 per each group. *p < 0.05 vs. control group