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Table 1 Characteristics of sham-operated (SHAM) and ovariectomized (OVX) rats with and without angiotensin II (AII) infusion

From: Significant role of female sex hormones in cardiac myofilament activation in angiotensin II-mediated hypertensive rats

 

Non AII Infusion

AII Infusion

SHAM (No.)

OVX (No.)

SHAM (No.)

OVX (No.)

Body weight (g)

298 ± 3

353 ± 7*

294 ± 3#

354 ± 3*,†

(14)

(12)

(13)

(14)

Heart weight (g)

1.47 ± 0.02

1.53 ± 0.04

1.56 ± 0.03*

1.77 ± 0.03*,#,†

(14)

(12)

(13)

(14)

Heart/body weight

0.47 ± 0.01

0.42 ± 0.01*

0.52 ± 0.01*,#

0.49 ± 0.01#,†

(14)

(12)

(13)

(14)

Uterine weight (g)

0.54 ± 0.02

0.14 ± 0.01*

0.54 ± 0.03#

0.13 ± 0.03*,†

(14)

(12)

(13)

(14)

Systolic pressure (mm Hg)

123 ± 2

121 ± 3

161 ± 9*,#

162 ± 4*,#

(5)

(6)

(5)

(6)

Diastolic pressure (mm Hg)

82 ± 3

81 ± 4

106 ± 6*,#

101 ± 4*,#

(5)

(6)

(5)

(6)

  1. Data are mean ± SE.*,# P < 0.05, significantly different from SHAM and OVX, respectively, using Student–Newman–Keuls test after ANOVA. P < 0.05, significantly different from SHAM + AII using unpaired t-test