Fig. 4

Effect of ovariectomy and angiotensin II (AII)-induced hypertension on cardiac myofilament Ca²⁺ sensitivity. a Relations of percentage of maximum active tension-pCa of skinned papillary muscle from SHAM and OVX rats, with/without AII, at two sarcomere lengths of 2.0 and 2.3 μm. b Comparison of the pCa₅₀ (pCa at the half maximum tension) among the four experimental groups at the two sarcomere lengths. Data are mean ± SE from 12 to 13 fibers of 7–8 hearts in each group. *^,†Significantly different (P < 0.05) from SHAM and SHAM + AII group at the same sarcomere length, respectively, using Student–Newman–Keuls test after ANOVA