Fig. 2

Effect of ovariectomy and angiotensin II (AII)-induced hypertension on cardiac myofilament Ca²⁺ activation. a Relations of active tension-pCa (−log[Ca²⁺]) of skinned papillary muscle from SHAM and OVX rats, with/without AII, at two sarcomere lengths of 2.0 and 2.3 μm. b Comparison of the maximum active tension among the four experimental groups at the two sarcomere lengths. Data are mean ± SE from 12 to 13 fibers of 7–8 hearts in each group. *^,†Significantly different (P < 0.05) from SHAM and SHAM + AII group at the same sarcomere length, respectively, using Student–Newman–Keuls test after ANOVA