Fig. 2
From: Effects of electroacupuncture on oxaliplatin-induced neuropathic cold hypersensitivity in rats
Effects of EA with different stimulation parameters on oxaliplatin-induced cold allodynia. The behavioral tests for cold allodynia were performed before and after the EA (2 or 100 Hz, ST36 acupoint or non-acupoint, 0.3-ms pulse width, 0.2–0.3 mA, for 20 min). a Control (light immobilization without EA, n = 8). b 2 Hz ST36 EA (low-frequency EA stimulation at ST36 acupoint, n = 13). c 100 Hz ST36 EA (high-frequency EA stimulation at ST36 acupoint, n = 10). d Non-acupoint EA (low-frequency EA stimulation at non-acupoint, n = 9). e Comparison of increase rate in withdrawal latency between ST36 EA (b) and non-acupoint EA (d) groups. Data are expressed as mean ± SEM. *P < 0.05, ***P < 0.001, by paired (a–d) or unpaired (e) t test