Fig. 1From: Role of PGE2 in the colonic motility: PGE2 generates and enhances spontaneous contractions of longitudinal smooth muscle in the rat colonEffects of basal PG production on the motility of longitudinal muscle (LM). The frequency and amplitude of GCs were measured in LM from the rat middle colon. After measuring spontaneous GCs, the bath solution was replaced, and 30 min later, piroxicam (10−5 M) was added. a A representative trace of spontaneous GCs (†), GCs after washing (‡), and GCs in the presence of piroxicam (10−5 M) (§). a and b Frequency and mean amplitude (c) of spontaneous GCs (†), GCs after washing (‡), and GCs in the presence of piroxicam (10−5 M) (§). Values are mean ± SEM (n = 211). The numbers in each column in (c) indicate the number of preparations, excluding preparations with an amplitude of 0. ***P < 0.001 and **P < 0.01 (Tukey–Kramer test)Back to article page