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Fig. 4 | The Journal of Physiological Sciences

Fig. 4

From: The mechanism of increased postnatal heart rate and sinoatrial node pacemaker activity in mice

Fig. 4

Membrane currents and current–voltage relationships of isolated single SAN cells from neonatal and adult mice. a Whole-cell current of a SAN cell of neonatal (upper traces) and adult mice (lower traces) in normal Tyrode’s solution. Traces shown were obtained by applying 500-ms depolarizing or hyperpolarizing pulses from a holding potential (V h) of −50 mV in 10-mV increments. Dashed lines indicate the zero current level. b Current–voltage relationships for the initial current (open circles neonate, filled circles adult) and the current near the end of the pulses (open squares neonate, filled squares adult). Data are mean ± SEM

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