Fig. 1
From: Interleukin-6 inhibits L-type calcium channel activity of cultured cerebellar granule neurons
Effect of IL-6 on whole-cell Ca-channel current in cultured CGNs. The whole-cell inward currents through the Ca channel were evoked by depolarization from −60 to +40 mV at a holding potential of −80 mV. A typical whole-cell inward Ca-channel current in control neuron (a) and in IL-6-pretreated neuron (b) was exhibited. Statistical analysis of current density displayed that the effect of IL-6 diminishing the Ca-channel current was significant between −20 and +10 mV of depolarization (c). *p < 0.05, **p < 0.01, compared with relative membrane potential of control (n = 10)