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Table 1 Characteristics of the subjects

From: Computational assessment of insulin secretion and insulin sensitivity from 2-h oral glucose tolerance tests for clinical use for type 2 diabetes

 

Subjects used in the evaluation of insulin secretion

Subjects used in the evaluation of insulin sensitivity

All

NGT

IGT

T2D

All

NGT

IGT

T2D

n

46

9

5

32

79

10

11

58

Age (years old)

50.4 ± 12.0

45.8 ± 14.3

46.4 ± 9.1

52.4 ± 11.5

53.1 ± 13.4

47.8 ± 15.0

49.7 ± 14.2

54.7 ± 12.9

Sex (male/female)

33/13

8/1

3/2

22/10

57/22

9/1

8/3

40/18

BMI (kg m−2)

26.2 ± 6.1

28.7 ± 8.6

26.0 ± 5.8

25.5 ± 5.3

25.6 ± 5.1

28.0 ± 8.4

26.3 ± 4.8

25.1 ± 4.3

G (0) (mg dl−1)

113.7 ± 25.1

83.9 ± 8.1

93.0 ± 13.9

125.4 ± 20.1

112.6 ± 21.6

84.4 ± 7.8

98.2 ± 13.8

120.1 ± 18.9

G (30) (mg dl−1)

205.7 ± 54.0

138.8 ± 29.8

179.6 ± 35.2

228.7 ± 43.5

202.9 ± 46.7

143.8 ± 32.3

188.0 ± 49.8

216.0 ± 39.5

G (60) (mg dl−1)

258.8 ± 78.0

157.2 ± 43.3

191.4 ± 21.1

297.9 ± 54.5

253.7 ± 64.8

157.5 ± 40.9

213.9 ± 35.8

277.8 ± 52.3

G (120) (mg dl−1)

254.8 ± 105.8

103.4 ± 19.0

154.2 ± 14.2

313.0 ± 65.9

254.4 ± 90.6

105.5 ± 19.0

162.1 ± 22.6

297.6 ± 60.4

I (0) (μU ml−1)

6.8 ± 6.6

11.5 ± 12.7

6.0 ± 2.5

5.7 ± 3.8

6.3 ± 5.8

10.7 ± 12.2

5.9 ± 4.3

5.6 ± 3.8

I (30) (μU ml−1)

35.1 ± 51.1

94.0 ± 89.6

35.5 ± 27.6

18.5 ± 17.9

28.7 ± 40.9

91.4 ± 84.9

29.5 ± 24.1

17.8 ± 15.5

I (60) (μU ml−1)

43.7 ± 50.5

110.0 ± 75.8

46.3 ± 23.3

24.7 ± 22.2

37.2 ± 41.1

104.2 ± 73.8

40.2 ± 24.4

25.1 ± 20.1

I (120) (μU ml−1)

44.0 ± 39.7

79.0 ± 61.9

56.3 ± 32.1

32.2 ± 25.3

41.1 ± 33.6

75.0 ± 59.7

44.2 ± 30.0

34.7 ± 24.1

SSIHGC (μU ml−1)

24.4 ± 24.8

56.4 ± 37.8

27.8 ± 9.0

14.9 ± 10.9

    

GIR/SSIHIC (mg kg−1 min−1 μU−1 ml)

0.064 ± 0.034

0.074 ± 0.046

0.081 ± 0.032

0.059 ± 0.030

0.063 ± 0.032

0.072 ± 0.044

0.079 ± 0.037

0.059 ± 0.027

  1. The G and I represent glucose and insulin concentrations during the OGTT, respectively. A subscript in parentheses represents a value at a time (min) after the oral glucose load. The SSIHGC and SSIHIC represent steady-state insulin concentrations during the HGC and the HIC, respectively. The GIR represents the steady-state glucose infusion rate during the HIC