Fig. 7

Effects of 4V or i.v. 3HB injection on plasma metabolites and catecholamines. Changes in plasma levels of glucose (a), 3HB (b), NEFA (c), NE (d), and epinephrine (e) after 3HB injection into the 4V (n = 4–6 per group) at 13:00 h in normal male rats. Changes in plasma levels of glucose (f), 3HB (g), and NEFA (h) after intravenous 3HB (16 μmol) injection (n = 4–6 per group) in normal male rats. Vehicle-treated controls were injected with artificial CSF. Statistical differences were determined by two-way ANOVA (treatment and time) followed by the Bonferroni test. *P < 0.05, **P < 0.01, ***P < 0.001, versus vehicle-treated controls. Values are means ± SEM