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Table 1 Lipid metabolism parameters of high fat diet induced obese rats, sham operated (S) or lipectomyzed (L), sacrificed 7 or 30 days after surgery

From: White adipose tissue re-growth after partial lipectomy in high fat diet induced obese Wistar rats

 

S7

L7

S30

L30

Body weight gain (%)

5.08 ± 0.83 a

0.59 ± 0.72 b

19.90 ± 1.27 c

17.64 ± 2.29 c

Energy intake (kJ)

3194 ± 179.9 a

2577 ± 152.9 b

3659 ± 65.3 c

3698 ± 83.5 c

Carcass

 Relative lipid content

3.2 ± 0.42 a

3.0 ± 0.30 a

3.6 ± 0.22 a

3.0 ± 0.36 a

 Lipogenesis rate

0.91 ± 0.05 a

0.92 ± 0.11 a

0.78 ± 0.05 a

1.07 ± 0.22 a

Liver

 Relative weight

3.42 ± 0.07 a

3.47 ± 0.08 a

2.81 ± 0.09 b

3.06 ± 0.13 b

 Relative lipid content

3.55 ± 0.15 a

3.76 ± 0.19 a

4.67 ± 0.24 b

4.19 ± 0.26 ab

 Lipogenesis rate

7.58 ± 0.75 a

19.78 ± 2.18 b

6.76 ± 1.29 a

7.36 ± 0.79 a

 Malic enzyme

0.25 ± 0.02 ab

0.27 ± 0.02 ab

0.15 ± 0.01 a

0.31 ± 0.02 b

BAT

 Relative weight

0.08 ± 0.006 a

0.09 ± 0.003 a

0.11 ± 0.004 b

0.11 ± 0.006 b

 Relative lipid content

47.14 ± 0.99 ab

51.75 ± 2.37 a

43.92 ± 3.39 b

48.40 ± 1.57 ab

 Lipogenesis rate

7.28 ± 1.10 a

6.69 ± 0.53 a

8.32 ± 1.09 a

12.08 ± 0.75 b

RET

 Total relative weight

1.09 ± 0.05 a

1.31 ± 0.20 a

1.34 ± 0.25 a

1.32 ± 0.16 a

 Lipogenesis rate

4.42 ± 0.65 a

5.09 ± 1.34 a

1.18 ± 0.12 b

2.36 ± 0.45 c

 Lipolysis rate

0.09 ± 0.02 a

0.18 ± 0.08 ab

0.17 ± 0.02 a

0.32 ± 0.04 b

 Nor-lipolysis rate

0.12 ± 0.05 a

0.29 ± 0.14 b

0.29 ± 0.07 b

0.32 ± 0.05 b

 Adipocyte area

8,678 ± 2,279 a

7,764 ± 1,011 a

13,005 ± 1,775 b

6,694 ± 726 a

EPI

 Total relative weight

1.01 ± 0.08 a

1.40 ± 0.13 b

1.22 ± 0.16 ab

1.27 ± 0.09 ab

 Lipogenesis rate

4.42 ± 0.95 ac

5.52 ± 1.45 a

1.09 ± 0.08 b

2.55 ± 0.36 c

 Lipolysis rate

0.04 ± 0.01 a

0.10 ± 0.03 ab

0.19 ± 0.02 b

0.20 ± 0.04 b

 Nor-lipolysis rate

0.06 ± 0.02 a

0.14 ± 0.04 b

0.15 ± 0.02 b

0.32 ± 0.05 c

 Adipocyte area

5,767 ± 605 a

6,777 ± 672 a

8,102 ± 614 a

6,972 ± 904 a

  1. Body weight gain (% at surgery) and energy intake (total kJ at the 1st or 4th week after surgery); carcass relative lipid content (g/100 g tissue) and lipogenesis rate (μmol of 3H2O incorporated into lipid/g of tissue); liver relative weight (g/100 g body weight), relative lipid content, lipogenesis rate and malic enzyme activity (μmol/min/100 mg liver); BAT relative weight, relative lipid content and lipogenesis rate; RET and EPI total relative weight (removed at surgery plus at sacrifice), lipogenesis rate, lipolysis rate (μmol of glycerol release/100 mg of adipose tissue), noradrenalin-stimulated lipolysis rate, adipocyte mean area (μm2)
  2. All results are presented as means ± standard error of the mean. The number of animals varied from 6 to 10. Values with different letters are significantly different from one another at p < 0.05