Fig. 3

Effects of intragastric infusion of umami substances on the efferent discharge rate of a vagal celiac nerve (VCE) and a sympathetic adrenal nerve (SAE) filament. a, b Examples of intragastric infusion of a 30 mM IMP and b 150 mM MSG on VCE activity. Arrowheads indicate points at which the umami substance solution was infused. The vertical bar indicates 100 impulses/5 s. The horizontal bar indicates 30 min. c Summary plot and summary of changes in discharge rate showing the impulse values of IMP and MSG on VCE activity measured before and after administration. Data from the same rat are connected by a line. Open and closed circles with bars represent the mean ± SEM. Columns and vertical bars represent mean changes in spike ±SEM. d, e Examples of intragastric infusion of d 30 mM IMP and e 150 mM MSG on SAE activity. Arrowheads indicate points at which the umami substance solution was infused. The vertical bar indicates 100 impulses/5 s. The horizontal bar indicates 30 min. f Summary plot and summary of changes in discharge rate showing the impulse values of IMP and MSG on SAE activity measured before and after administration. Data from the same rat are connected by a line. Open and closed circles with bars represent the mean ± SEM. Columns and vertical bars represent mean changes in spike ±SEM. *p < 0.05, **p < 0.01, paired t test