Fig. 4

Proliferative effect of LPS on splenic lymphocytes from control (n = 7 per group) and alloxan-induced diabetic (n = 7 per group) mice. Lymphocytes were stimulated for 72 h with various concentrations of LPS, and proliferation was measured by MTT assay. The net ΔOD₅₇₀ is the difference between the increase in OD₅₇₀ (optical density at 570 nm) at 72 h after addition of LPS and the vehicle. Data express group mean ± SEM (7 independent experiments performed in duplicate)