Fig. 2
a Time course of changes in [Ca2+]i in response to LPS (40 μg/ml) in splenic lymphocytes from control and alloxan-induced diabetic mice. b Effects of LPS on [Ca2+]i in splenic lymphocytes from control (n = 7 per group) and alloxan-induced diabetic (n = 7 per group) mice. Fura-2-loaded lymphocytes were incubated for 8 min with or without LPS. The net Δ[Ca2+]i is the difference between the increase in [Ca2+]i at 8 min after addition of LPS and the vehicle. Data express group mean ± SEM (7 independent experiments performed in duplicate)