Fig. 4

BMP-1/mTLD and TLL1 mRNA levels in the TA and SOL muscles in response to food deprivation. a TA BMP-1/mTLD mRNA levels, b TA TLL1 mRNA levels, c SOL BMP-1/mTLD mRNA levels, d SOL TLL1 mRNA levels relative to β-actin in control (fed), 2-day food deprived (food-deprived) and 2-day food-deprived then refed for 2 days (refed) mice. Expression of TLL1 mRNA was significantly decreased in TA and SOL of food deprived animals and remained significantly decreased in the TA, but not SOL, following 2 days of refeeding. All results are reported as mean ± SEM of mRNA levels normalized to those of β-actin and relative to the fed control. Asterisk significantly different from fed control, p < 0.05. See Fig. 1 for the abbreviations used