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Fig. 3 | The Journal of Physiological Sciences

Fig. 3

From: A stable ATP binding to the nucleotide binding domain is important for reliable gating cycle in an ABC transporter CFTR

Fig. 3

Kinetic parameters of macroscopic current relaxations for Y1219G, Y1219I, Y1219F and Y1219W. a Time constants of the slow component of the current relaxation for the Y1219 mutants. Y1219G: n = 5; Y1219I: n = 7; Y1219F: n = 4; and Y1219W: n = 5. b Fraction of the slow component (A slow/A slow + A fast) for the Y1219 mutants. Y1219G: n = 5; Y1219I: n = 7; Y1219F: n = 4; and Y1219W: n = 5

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