Fig. 6From: Spirometric and flow-volume curve analysis in rats, and optimal parameters for estimating obstructive impairmentWith an increase in the concentration of inhaled Mch (methacholine), PEFR (a), FVC (filled circles in b), FEV0.10 (filled circles in c), and FEV0.05 (open circles in c) gradually decreased while FEV0.1/FVC (filled circles in d) and FEV0.05/FVC (open circles in d) progressively increased. The inflection point between the second and third phases (open circles in b) and the position of the peak point (open diamonds in b) on forced expiratory volume are also shown. Values are mean ± SD. $P < 0.05 versus 0, *P < 0.05 versus 0.5, #P < 0.05 versus 1.0, +P < 0.05 versus 2.0Back to article page