Fig. 4
From: Estrogen modulates central and peripheral responses to cold in female rats
Counts of c-Fos-immunoreactive cells in the hypothalamic areas. Counts of cFos-IR cells in the hypothalamic areas after 25°C exposure in Experiment 1 (A), 5°C exposure in Experiment 1 (B), 25°C exposure in Experiment 2 (C),and 5°C exposure in Experiment 2 (D). Values are given as the mean ± SE [A n = 7 (4 in the E2 (+) group and 3 in the E2 (−) group), B n = 25 (15 in the E2 (+) group and 10 in the E2 (−) group), C n = 16 (7 in the P group and 9 in the D1 group), D n = 20 (10 in the P group and 10 in the D1 group)]. *Significant difference between the E2 (+) and E2 (−) groups or the P and D1 groups, P < 0.05. MnPO Median preoptic nucleus, VMH ventromedial hypothalamus, T a ambient temperature