Fig. 1
From: Estrogen modulates central and peripheral responses to cold in female rats
Changes in body core temperature (T b) at 25°C (A, C), and 5°C (B, D) in Experiments 1 and 2, respectively. T b is shown as the 5-min average during a 2-h exposure at 5 or 25°C after a 2-h baseline at 25°C. Values are given as the mean ± standard error (SE) [A n = 25 (11 in the E2 (+) group and 14 in the E2 (−) group), B n = 30 (15 in the E2 (+) group and 15 in the E2 (−) group), C n = 16 (7 in the P group and 9 in the D1 group), D, n = 20 (10 in the P group and 10 in the D1 group)]. *Significant difference between the E2 (+) and E2 (−) groups or between the P and D1 groups at P < 0.05. #Significant difference from the baseline value, P < 0.05. E 2 17β-estradiol, P proestrus, D 1 first day of diestrus