Fig. 8

Combination pattern of BIS and BIT. a Optical action potentials detected simultaneously from three different positions (a–c). This event of BIS was observed 2 h after the application of Bleb (100 μM). b Optical mapping of the excitation spread. The first action potential spread toward the surrounding area from the anomalous pacemaker near the lower edge (left map). The second action potential appeared from the two anomalous foci indicated by F1 and F2 and spread in the limited area of the preparation (right map). Other symbols are as defined in Figs. 1, 3, 4, and 6. See text for details