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Fig. 4 | The Journal of Physiological Sciences

Fig. 4

From: Effect of the cholinesterase inhibitor donepezil on cardiac remodeling and autonomic balance in rats with heart failure

Fig. 4

a A representative example of time series of RR interval (left) and its power spectrum (right) in a donepezil-treated rat. RR intervals shown with dotted lines were assessed to be extrasystoles or post-extrasystoles and were removed before the power spectrum was calculated. Solid area indicates the high-frequency (HF) component. b HF of heart rate variability during the day. No significant difference in daytime HF value was observed between the donepezil group (shaded bar, D) and the nontreated group (open bar, N). c HF component of heart rate variability during the night. The nocturnal HF value of the donepezil group (shaded bar, D) was significantly higher than that of the nontreated group (open bar, N). *P < 0.05 by t test using log(HF) values

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