Fig. 1
a Schematic representation of the experimental design. Electrocardiogram (ECG) was recorded continuously using a telemetric system. b Ventricular sections of representative animals at week 6 of treatment (8 weeks post-infarction). No significant difference in the size of the myocardial infarction was observed between the donepezil group and the nontreated group. Compared with the nontreated heart (N), the donepezil-treated heart (D) had a thicker scar in the infarct area with more spared myocardium in the border area. c Combined weight of left and right ventricles per body weight (HW/BW) at week 6 of treatment. Ventricular weight was significantly lower (*P < 0.05) in the donepezil group (shaded bar, D) than in the nontreated group (open bar, N)