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Table 1 Effects of intravenous angiotensin II (ANG II) on the parameters of logistic functions and regression lines of the open-loop baroreflex characteristics

From: High levels of circulating angiotensin II shift the open-loop baroreflex control of splanchnic sympathetic nerve activity, heart rate and arterial pressure in anesthetized rats

 

Control 1

Control 2

ANG II

Total baroreflex, CSP–AP relation

 P 1 (mmHg)

56.2 ± 7.2

56.3 ± 6.4

49.7 ± 6.2

 P 2 (mmHg−1)

0.116 ± 0.019

0.118 ± 0.015

0.094 ± 0.013

 P 3 (mmHg)

129.2 ± 3.5

124.5 ± 2.8

125.7 ± 3.2

 P 4 (mmHg)

67.6 ± 4.6

69.7 ± 5.8

101.4 ± 10.9**,††

 Maximum gain

1.57 ± 0.28

1.58 ± 0.22

1.20 ± 0.25

Baroreflex control of HR, CSP–HR relation

 P 1(beats/min)

41.7 ± 5.1

43.9 ± 6.2

51.2 ± 3.8

 P 2 (mmHg−1)

0.123 ± 0.027

0.133 ± 0.018

0.099 ± 0.013

 P 3 (mmHg)

131.8 ± 3.8

125.8 ± 3.6

129.1 ± 2.6

 P 4 (beats/min)

391.1 ± 13.7

388.0 ± 12.6

417.4 ± 11.5**,††

 Maximum slope (beats min−1 mmHg−1)

1.11 ± 0.12

1.39 ± 0.23

1.28 ± 0.19

Neural arc, CSP–SNA relation

 P 1 (%)

69.6 ± 5.7

66.5 ± 7.4

78.9 ± 9.1

 P 2 (mmHg−1)

0.110 ± 0.016

0.124 ± 0.015

0.098 ± 0.011

 P 3 (mmHg)

133.2 ± 3.8

127.3 ± 3.1

126.0 ± 3.4*

 P 4 (%)

33.3 ± 5.4

35.0 ± 6.4

56.5 ± 11.5*,†

 Maximum slope (%/mmHg)

1.94 ± 0.34

2.02 ± 0.33

2.04 ± 0.42

Peripheral arc, SNA–AP relation

 Slope, a (mmHg/%)

0.85 ± 0.09

0.86 ± 0.06

0.66 ± 0.10

 Intercept, b (mmHg)

37.8 ± 5.2

36.9 ± 5.5

68.0 ± 10.6**,††

 AP at 100% SNA (mmHg)

122.7 ± 9.9

122.7 ± 7.0

134.4 ± 4.9

Operating point

 AP (mmHg)

111.4 ± 5.0

110.3 ± 5.1

128.1 ± 4.4**,††

 SNA (%)

90.6 ± 7.4

85.8 ± 2.1

94.3 ± 5.9

  1. Data are mean and SE values
  2. CSP Carotid sinus pressure, AP arterial pressure, HR heart rate, SNA sympathetic nerve activity
  3. * P < 0.05 and **P < 0.01 from control 1, † P < 0.05 and †† P < 0.01 from control 2