Fig. 2

EMG analysis of limb-withdrawal responses to mechanical, thermal, and cold stimuli in neuropathic rat. a The EMG magnitude of the limb-withdrawal reflexes and the intensity of the von Frey filament in normal and neuropathic rats. b The EMG magnitude of the hindlimb-withdrawal responses following thermal stimuli in normal and neuropathic rats. c The EMG magnitude of the hindlimb-withdrawal responses to acetone (cold stimulation). The gray line in each figure represents the minimum EMG magnitude value (0.1 mV) that showed abrupt hindlimb-withdrawal reflexes (painful response) to stimuli. Data are mean ± SEM. *P < 0.05 versus the normal group