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Table 1 Changes in body weight, kidney weight, blood pressure, urinary protein excretion and renal function after uninephrectomy with or without tempol

From: Reactive oxygen species mediate compensatory glomerular hypertrophy in rat uninephrectomized kidney

 

0 h

1 week

2 weeks

Nx

Nx + TP

Nx

Nx + TP

Nx

Nx + TP

BW (g)

221 ± 13

218 ± 10

308 ± 9

311 ± 9

345 ± 10

329 ± 11

MBP (mmHg)

73.5 ± 3.5

72.8 ± 3.3

74.5 ± 1.9

71.2 ± 2.6

76.0 ± 3.2

73.0 ± 2.4

Ccr (ml/min)

3.1 ± 0.3

3.0 ± 0.4

2.4 ± 0.2

2.2 ± 1.4

2.3 ± 0.3

2.1 ± 0.4

UPE (mg/day)

1.1 ± 0.3

1.2 ± 0.5

1.2 ± 0.4

1.5 ± 0.2

1.3 ± 0.3

1.5 ± 0.3

KW/BW (mg/g)

4.7 ± 0.2

4.9 ± 0.4

6.0 ± 0.2

5.7 ± 0.1*

6.3 ± 0.3

5.4 ± 0.3*

  1. N = 8 in each group. Data are expressed as mean ± SEM. BW body weight, MBP mean blood pressure, Ccr creatinine clearance, UPE urinary protein excretion, KW kidney weight. *P < 0.05 versus Nx
  2. BW body weight, MBP mean blood pressure, Ccr creatinine clearance, UPE urinary protein excretion, KW kidney weight
  3. *P < 0.05 versus Nx
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The Journal of Physiological Sciences

ISSN: 1880-6562

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