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Fig. 2 | The Journal of Physiological Sciences

Fig. 2

From: Endocrine profile and testicular histomorphometry in adult rat offspring of diabetic mothers

Fig. 2

Section of testes showing interstitial tissue (Leydig cells) of 90-day-old rat. H&E staining. B1 Offspring from normal mother, B2 offspring from diabetic mother, ×2000. Arrows indicate the location of Leydig cells. Leydig cells in offspring from normal mother rats presented a characteristic appearance, with a very active nucleus, as shown by the presence of a decondensed chromatin and several nucleoli (B1). In contrast, in offspring from diabetic mother rats, B2 Leydig cells were scarce and showed a highly vacuolated cytoplasm. Furthermore, the nuclei of the cells were of irregular shape, and the chromatin content had a distinct appearance

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