Fig. 3
From: Factors affecting SOCE activation in mammalian skeletal muscle fibers
Reversibility of the CPA effect on the SR Ca2+ pump. The three runs in the figure, carried out with different fibers, show that following the depletion procedure, washing out CPA at different times: a after, b simultaneously or c before activating SOCE with 5 mM Ca2+, rapidly reverses or reduces the [Ca2+]myo. The results demonstrate that the unpoisoned SR Ca2+ pump effectively competes with SOCE