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Fig. 2 | The Journal of Physiological Sciences

Fig. 2

From: Endogenous angiotensin II has fewer effects but neuronal nitric oxide synthase has excitatory effects on renal sympathetic nerve activity in salt-sensitive hypertension-induced heart failure

Fig. 2

Recordings obtained from a CHF-DSS rat in the control, SMTC, and SMTC+losartan phases. Control: before any drugs; SMTC: 40 min after intravenous S-methyl-l-thiocitrulline (SMTC, 10 mg/kg); SMTC+losartan: 60 min after intravenous losartan (10 mg/kg) following intravenous SMTC. Occ: caval occlusion to decrease arterial pressure at a rate of 3–5 mmHg/s. AP arterial pressure, MAP mean arterial pressure, HR heart rate, RSNA renal sympathetic nerve activity, Int RSNA integrated RSNA. Each arrow indicates a peak response of mean RSNA to a ramp decrease in AP by caval occlusion

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