Fig. 4

Effects of pharmacologic inhibition of nNOS by L-VNIO and genetic deletion of nNOS on IP-induced reduction of cardiac infarct size. Cardiac infarct size was measured as described in “Methods”. Data are expressed as mean percentage of infarct size to risk area. Open circles represent individual mice whereas solid circles represent mean ± SEM. ¶P < 0.05 compared with the WT IR group, †P < 0.05 compared with the WT IP group