Fig. 4
From: Late Na+ current produced by human cardiac Na+ channel isoform Nav1.5 is modulated by its β1 subunit
Effect of β1 subunit on the steady-state inactivation (SSI) voltage-dependency of the heterologous expressed Nav1.5. a, b Representative raw current recordings at −30 mV in response to a different 2-s-long prepulse potential (voltage procedure is shown in c). c Data points of the relative (normalized to maximum) peak I NaT measured at −30 mV and plotted against prepulse voltage (V p). Solid lines represent the Bolzmann fit (Eq. 2 in “Methods”), and values are given on the plots. Statistics for values evaluated in numerous cells are given in Table 1. V h = −140 mV, [Na]0 = 140 mM, 24°C