Variable | CTR N = 12 | CTR + S N = 12 | SHAM N = 16 | LVH N = 12 | LVH + S N = 12 |
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Body weight (g) | 405.4 (27.1) | 499.2** (41.4) | 411.1 (29.1) | 396.1 (45.0) | 459.4* (29.1) |
Heart weight (g) | 1.04 (0.09) | 1.18* (0.11) | 1.07 (0.11) | 1.09 (0.10) | 1.12 (0.08) |
LV weight (g) | 0.48 (0.06) | 0.60* (0.08) | 0.48 (0.05) | 0.57* (0.07) | 0.59* (0.06) |
LV/BW (mg/g) | 1.19 (0.14) | 1.20 (0.11) | 1.16 (0.11) | 1.44** (0.08) | 1.28$ (0.09) |
- Data are means (SD)
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LV left ventricle, BW body weight
- CTR, controls; SHAM, sham-operated controls; LVH, animals with pressure-overload-induced left ventricular hypertrophy
- CTR + S, control animals subjected to electrically induced tachycardia; LVH + S, animals with pressure overload-induced LV hypertrophy subjected to electrically stimulated tachycardia
- * P < 0.05 and ** P < 0.001 versus the appropriate controls (CTR or SHAM); $ P = 0.08 versus SHAM