Fig. 6

l-Arg-induced NO release at different pH levels in furosemide-pretreated NE-MD cells. a Representative traces of NO release at pH 7.6 (top), 7.4 (middle), and 7.1 (bottom). Arrows and arrowheads indicate the same meanings shown in Fig. 1. b NOs released are 12.1 ± 1.1 (pH 7.1), 51.1 ± 10.0 (pH 7.4), and 45.5 ± 13.6 nM (pH 7.6) in the presence of 1 mM l-Arg (n = 3, each column). Statistical significance was obtained by comparison with control values (pH 7.4)