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Table 2 Comparison of the single-channel properties between the mitochondrial VDAC and the maxi-anion channel

From: The maxi-anion channel: a classical channel playing novel roles through an unidentified molecular entity

Parameter VDAC Maxi-anion channel
PCl/PK (100/1,000 mM KCl) 1.7–1.9 [173, 174] 13.5 ± 2.3 [14]
Pacetate/PCl 0.41 [178] 0.58 ± 0.01 [14]
Pglutamate/PCl 0.4 [175] 0.17 [108]; 0.23 [14]
[Cl] dependence for single-channel conductance Linear up to 10 nS with no saturation [173] Saturates at 580–640 pS with Kd = 77–120 mM [24, 104, 113]
Pore size 1 and 2 nm for different entrances [179, 180] 1.16 and 1.42 nm for different entrances [11]
Voltage-dependent “closed” state Retains ~40% of initial conductance [150] Non-conductive [8, 14]