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Fig. 4 | The Journal of Physiological Sciences

Fig. 4

From: The maxi-anion channel: a classical channel playing novel roles through an unidentified molecular entity

Fig. 4

Maxi-anion channel has a wide pore larger than the size of ATP. Left panels Basic principle of the polymer partitioning method using PEGs (depicted as globules) of different sizes (upper panel) and the effective pore radius (R) of an ATP molecule calculated in two different conformations: conventional long and more compact forms found in crystals (see for details: Sabirov and Okada [11]). Right panel Relative single maxi-anion channel conductance (circles) and relative bulk solution conductivity (triangles) as a function of the hydrodynamic radius of PEGs. Each symbol represents the mean ± SEM (vertical bar) (n = 5–20). Pore size is estimated as an intersection point between a rising portion of the curve (partial partitioning) and an upper plateau level (complete exclusion). Modified from Sabirov and Okada [11]

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