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Fig. 4 | The Journal of Physiological Sciences

Fig. 4

From: Increased O2 consumption in excitation–contraction coupling in hypertrophied rat heart slices related to increased Na+–Ca2+ exchange activity

Fig. 4

Effects of CPA, CPA + KBR and CPA + KBR + CE on E–C coupling mVO2 in CONT (a) (n = 10–12 sets from 5–6 hearts) and HYP (b) slices (n = 8–14 sets from 4–7 hearts). Each bar shown in a and b was not series data. Ordinate axis: E–C coupling mVO2 values by each second measurement. c Origin of E–C coupling mVO2 in CONT and HYP slices shown in a and b. SERCA2: sarcoplasmic reticulum Ca2+-ATPase. NCX: Na+/Ca2+ exchanger. NHE: Na+/H+ exchanger *P < 0.01 vs. None. # P < 0.01 vs. CPA. P < 0.05 vs. None in CONT slices. P < 0.01 vs. CPA in CONT slices. § P < 0.05 vs. CPA + KBR in CONT slices

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